Sulfur Co-doped Carbon Quantum Dots Research Articles

Detection of ferric ions by nitrogen and sulfur co-doped potato-derived carbon quantum dots as a fluorescent probe

This paper reports the detection of ferric ions (Fe3+) based on nitrogen and sulfur co-doped carbon quantum dots. These nitrogen and sulfur co-doped carbon quantum dots were synthesized via a hydrothermal route using northern Shaanxi potatoes as carbon sources and ammonium sulfate as nitrogen and sulfur sources. The quantum yields of the carbon quantum dots were found to be 16.96% and 4.23% with and without doping, respectively. The structural details, morphology, and optical properties of carbon quantum dots were analyzed using Fourier transform infrared spectroscopy (FT-IR), x-ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM), ultraviolet-visible absorption spectroscopy (UV–vis), and fluorescence spectroscopy. The as-prepared co-doped carbon quantum dots were utilized as a fluorescent probe for detecting Fe3+ ions, where the fluorescence intensity of carbon quantum dots was remarkably quenched in the presence of Fe3+ ions. A good linear relationship for Fe3+ ion detection was obtained from 0 to 500 μmol/L with a detection limit as low as 0.26 μmol/L. Furthermore, the proposed method also provided satisfactory results in the tap water.

One-pot Microwave Synthesis of Cobalt, Nitrogen, and Sulfur Co-Doped Carbon Quantum Dots for Efficient Monosodium Glutamate Determination in Food Samples

The synthesis of cobalt, nitrogen and sulfur co doped carbon quantum dots (Co-NS-CQDs) has become a subject of significant research interest. These CQDs were produced using a single-step microwave method, which is considered environmentally friendly, and the entire process was completed in just 90 seconds. In this synthesis, citric acid was utilized as the carbon source, methionine served as the source for both nitrogen and sulfur, and cobaltous acetate was used to introduce cobalt ions into the CQDs structure. The synthesized carbon quantum dots (CQDs) exhibit a narrow size distribution and a high quantum yield of 51.5%, which is notably superior to non-metal-doped CQDs with a yield of 38%. Characterization of these CQDs was performed using different techniques such as transmission electron microscopy (TEM), high-resolution TEM (HRTEM), Fourier transformation infrared spectroscopy (FTIR), energy dispersive X-ray analysis (EDX), X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). The developed CQDs have blue luminescence at emission wavelength 438 nm after excitation at 350 nm. Different factors affecting the CQDs synthesis including dialysis duration, reaction time and reaction temperature. These CQDs were utilized as a probe for the detection of monosodium glutamate (MSG) in various food products. The intensity of the fluorescence of the CQDs showed a direct and linear increase with the concentration of MSG within the range of 25–250 µg/mL. The detection and quantitation limits for MSG were 2.78 µg/mL and 8.44 µg/mL, respectively. Additionally, the developed method is environmentally friendly, as confirmed by assessments using the analytical Eco scale, Green Analytical Procedure Index (GAPI), and Analytical Greenness calculator (Agree). The proposed method presents several advantages over other reported methods in terms of convenience, rapid response, and attainment of accurate and precise results.

Photoelectrochemical quenching-recovery biosensor based on NSCQDs/Fe2O3@Bi2S3 for the detection of trypsin

BackgroundThe content of trypsin will change when pancreatic diseases occur, therefore developing a high-performance method for trypsin detection is of great significance for guiding patients on medication plans and improving their prognosis. Photoelectrochemical (PEC) analysis techniques have emerged as a solution to apply for bioassays. ResultsHerein, the Fe2O3@Bi2S3 and Nitrogen and sulfur co-doped carbon quantum dots (NSCQDs) were successfully synthesized by a hydrothermal method. Subsequently, NSCQDs/Fe2O3@Bi2S3 with a photocurrent amplification effect covered on fluorine-doped tin oxide (FTO) electrode as the substrate material and apoferritin (APO) as a bio-recognition element to quench the photocurrent of the substrate material which can be excited with light. Due to the decomposition specifically between APO and trypsin, the photocurrent response increased. The linear range for trypsin detection showed satisfied results from 2 to 1000 ng mL−1 under optimal conditions, with a detection limit of 0.42 ng mL−1 and a recovery rate of 97.41 %–103.02 %, enabling efficient quantitative analysis of trypsin. SignificanceIn this experiment, a PEC biosensor with simple operation, low detection limit, excellent selectivity and strong stability was successfully prepared, enabling quantitative analysis of trypsin in human serum samples through the quenching-recovery mechanism. It holds great significance for diagnosis and serves as a practical method for the detection of trypsin in the future.

Optimization, Kinetics, and Thermodynamics Study on the Degradation of RhB by ZnO Modified with Nitrogen and Sulfur Co-Doped Carbon Quantum Dots

Optimization, Kinetics, and Thermodynamics Study on the Degradation of RhB by ZnO Modified with Nitrogen and Sulfur Co-Doped Carbon Quantum Dots

Nitrogen and Sulfur Co-doped Carbon Quantum Dots for Detecting Fe3+, Ascorbic Acid and Alkaline Phosphatase Activities

Nitrogen and Sulfur Co-doped Carbon Quantum Dots for Detecting Fe3+, Ascorbic Acid and Alkaline Phosphatase Activities

Rapid environmentally benign label free detection of heparin using highly fluorescent N,S-CDs sensing probe through a turn-on mechanism

Heparin (HEP) is one of the oldest anticoagulant drugs that currently still in widespread clinical use. It lacks chromophore and not easily derivatized due to its hydrophilic nature. In this work we developed a green, selective, and sensitive fluorescence sensor for detection of HEP in its injection dosage forms. The sensor is composed of nitrogen and sulfur co-doped carbon quantum dots (N,S-CDs) semi quenched by Fe3+. The N,S-CDs were prepared using microwave assisted pyrolysis in 3.5 min and exhibited high emission at 425 nm after excitation at 350 nm with high quantum yield of 96%. Owing to the anionic nature of HEP, it could compete with N,S-CDs for Fe3+ complexation resulting in turning-on the quenched fluorescence. This fluorescence enhancement was linear over a concentration range between 6 and 20 μg/mL (R2 = 0.99) with a limit of detection of 1.41 µg/ml. The accuracy and precision of the proposed sensor were indicated by percentage recovery values between 98% −102% and %RSD less than 2, respectively. Furthermore, the proposed sensor was successfully applied for determination of HEP in injection dosage form. The developed sensor showed excellent greenness on analytical eco-scale (score 93%) and GAPI scale.

Nitrogen and sulfur co-doped coal-based carbon quantum dots enhance the photocatalytic hydrogen evolution of Co-Fe-P derived from MOF

In order to explore the functional application of coal and realize the high-value application of low-quality coal. Therefore, low-cost coal as a carbon source into environmental protection, high-value coal-based carbon quantum dots (CQDs). This study employed high-sulfur coal as the carbon source and urea as the nitrogen source to successfully synthesize nitrogen and sulfur co-doped coal-based carbon quantum dots (NSCQDs) via a one-pot hydrothermal method. These NSCQDs were utilized as co-catalysts to assist the photocatalytic water splitting and hydrogen evolution of metal phosphides (Co-P and Fe-P). The obtained catalysts were subjected to systematic structural and property analyses, and the photocatalytic hydrogen evolution activity and stability were investigated, along with an analysis of the photocatalytic mechanism. The results revealed that the novel composite photocatalyst exhibited high hydrogen evolution activity, with a maximum hydrogen evolution rate of 28.41 mmol·g−1·h−1 at pH 10. Under a wavelength of 520 nm, the apparent quantum efficiency (AQE) reached 4.93%, and the solar-to-hydrogen (STH) conversion efficiency reached 0.46%. The semiconductor type (n-type) of the monophasic catalyst was determined through Mott-Schottky analysis, and the band structure was analyzed accordingly. The conduction and valence band positions for Co-P were determined to be -0.44 eV and 1.31 eV, respectively, while those for Fe-P were found to be -0.51 eV and 1.17 eV, respectively. Based on these results, it is inferred that an S-type heterojunction is formed between Co-P and Fe-P, and NSCQDs enhanced photocatalytic hydrogen evolution as an auxiliary catalyst. This research advances the synthesis of coal-based carbon quantum dots and provides the key information for the photocatalytic decomposition of water and hydrogen evolution using coal-based CQDs.

Facile synthesis of nitrogen, sulfur co-doped carbon quantum dots for selective detection of mercury (II)

Facile synthesis of nitrogen, sulfur co-doped carbon quantum dots for selective detection of mercury (II)

Facile synthesis of NS-doped carbon dots as sensitive “ON-OFF-ON” fluorescent sensor for Cu2+ and GSH detection

In this paper, a novel nitrogen and sulfur co-doped carbon quantum dots (NS-CQDs) were successfully prepared by a dehydration exothermic carbonization method. The NS-CQDs exhibited uniform size distribution, splendid photostability, and bright fluorescence emission with a fluorescence quantum yield of 24.1 %. It was found that Cu2+ could quench the fluorescence at 467 nm based on the static quenching effect when Cu2+ was added to the NS-CQDs. At this time, the fluorescence sensor changed from the “ON” state to the “OFF” state. When glutathione (GSH) was further introduced into the NS-CQDs/Cu2+ system, the fluorescence intensity of NS-CQDs was amazingly restored through the coordination reaction between GSH and Cu2+. The fluorescence sensor changed from the “OFF” state to the “ON” state. Therefore, NS-CQDs as an “ON-OFF-ON” fluorescence sensor was designed for sequential detection of Cu2+ and GSH. Furthermore, this study successfully demonstrated the sensor’s ability to selectively detect Cu2+ and GSH within a wide concentration range. Specifically, the detection range for Cu2+ was 0.1 μM−200.0 μM with a detection limit of 0.07 μM, while the range for GSH was 0.6 μM−180.0 μM with a detection limit of 0.1 μM. Most importantly, the NS-CQDs nanosensor could reliably monitor Cu2+ and GSH levels in human serum samples, with significant potential for practical applications.

Enhanced photocatalytic hydrogen production from Co-MOF/CN by nitrogen and sulfur co-doped coal-based carbon quantum dots

A novel composite photocatalyst for photocatalytic decomposition of water for hydrogen evolution was successfully synthesized by in-situ growth of nitrogen and sulfur co-doped coal-based carbon quantum dots (NSCQDs) nanoparticles on the surface of sheet cobalt-based metal-organic framework (Co-MOF) and graphitic carbon nitride (g-C3N4, CN). The structure and properties of the obtained catalysts were systematically analyzed. NSCQDs effectively broaden the absorption of Co-MOF and CN in the visible region. The new composite photocatalyst has high hydrogen production activity and the hydrogen production rate reaches 6254 μmol/(g·h) at pH = 9. At the same time, NSCQDs synergy Co-MOF/CN composites have good stability. After four cycles of hydrogen production, the performance remains relatively stable. The transient photocurrent response and Nyquist plot experimental results further demonstrate the improvement of carrier separation efficiency in composite catalysts. The semiconductor type (n-type semiconductor) of the single-phase catalyst was determined by the Mott–Schottky test, and the band structure was analyzed. The conductive and valence bands of CN are −0.99 and 1.72 eV, respectively, and the conduction and valence bands of Co-MOF are −1.85 and 1.33 eV, respectively. The mechanism of the photocatalytic reaction can be inferred, that is, Z-type heterojunction is formed between CN and Co-MOF, and NSCQDs was used as cocatalyst.

Green “turn-off” luminescent nanosensors for the sensitive determination of desperately fluorescent antibacterial antiviral agent and its metabolite in various matrices

Nitazoxanide (NTX) is an antimicrobial drug that was used for the treatment of various protozoa. However, during the coronavirus pandemic, NTX has been redirected for the treatment of such virus that primarily infect the respiratory tract system. NTX is now used as a broad-spectrum antiviral agent. In this study, a highly sensitive and green spectrofluorometric method was developed to detect NTX in various dosage forms and its metabolite, tizoxanide (TX), in human plasma samples using nitrogen and sulfur co-doped carbon quantum dots nanosensors (C-dots). A simple and eco-friendly hydrothermal method was used to synthetize water soluble C-dots from citric acid and l-cysteine. After excitation at 345 nm, the luminescence intensity was measured at 416 nm. Quenching of C-dots luminescence occurred upon the addition of NTX and was proportional to NTX concentration. Assessment of the quenching mechanism was performed to prove that inner filter effect is the underlying molecular mechanism of NTX quenching accomplished. After optimizing all experimental parameters, the analytical procedure was evaluated and validated using the ICH guidelines. The method linearity, detection and quantification limits of NTX were 15 × 10–3–15.00 µg/mL, 56.00 × 10–4 and 15 × 10–3 µg/mL, respectively. The proposed method was applied for the determination of NTX in its commercial pharmaceutical products; Nanazoxid® oral suspension and tablets. The obtained % recovery, relative standard deviation and % relative error were satisfactory. Comparison with other reported spectrofluorimetric methods revealed the superior sensitivity of the proposed method. Such high sensitivity permitted the selective determination of TX, the main metabolite of NTX, in human plasma samples making this study the first spectrofluorimetric method in literature that determine TX in human plasma samples. Moreover, the method greenness was assessed using both Eco-Scale and AGREE approaches to prove the superiority of the proposed method greenness over other previously published spectrofluorimetric methods for the analysis of NTX and its metabolite, TX, in various dosage forms and in human plasma samples.

Rapid microwave synthesis of N and S dual-doped carbon quantum dots for natamycin determination based on fluorescence switch-off assay

Green, one-pot, quick, and easily synthesized nitrogen and sulfur co-doped carbon quantum dots (N,S-CDs) were obtained from cheap and readily available chemicals (sucrose, urea, and thiourea) using a microwave-assisted approach in about 4 min and utilized as a turn-off fluorescent sensor for estimation of natamycin (NAT). First, the effect of N and S doping on the microwave-synthesized CDs’ quantum yield was carefully studied. CDs derived from sucrose alone failed to produce a high quantum yield; then, to increase the quantum yield, doping with heteroatoms was carried out using either urea or thiourea. A slight increase in quantum yield was observed upon using thiourea with sucrose, while an obvious enhancement of quantum yield was obtained when urea was used instead of thiourea. Surprisingly, using a combination of urea and thiourea together results in N,S-CDs with the highest quantum yield (53.5%), uniform and small particle size distribution, and extended stability. The fluorescent signal of N,S-CDs was quenched upon addition of NAT due to inner filter effect and static quenching in a manner that allowed for quantitative determination of NAT over a range of 0.5–10.0 μg ml−1 (LOD = 0.10 μg ml−1). The N,S-CDs were applicable for determination of NAT in aqueous humor, eye drops, different environmental water samples, and bread with excellent performance. The selectivity study indicated excellent selectivity of the prepared N,S-CDs toward NAT with little interference from possibly interfering substances. In-silico toxicological evaluation of NAT was conducted to estimate its long-term toxicity and drug-drug interactions. Finally, the preparation of N,S-CDs, and analytical procedure compliance with the green chemistry principles were confirmed by two greenness assessment tools.

N, S-doped carbon quantum dot for long persistence phosphor assisted all-weather solar cells

Traditional solar cells can only work during the daytime. The solar cells that can harvest energy in all weather conditions are favorable to solving the energy crisis and ecological issues. We present a novel quantum dot-sensitized all-weather solar cell (AW-SC) that can harvest energy in both day and night conditions. The AW-SC consists of a TiO2/long persistence phosphor (LPP) photoanode sensitized by nitrogen and sulfur co-doped carbon quantum dots (N, S-CQDs) and a Pt counter anode. The N and S doping reduces the band gap of CQDs and enhances the charge injection into the TiO2 layer, resulting in better solar cell performance. The LPP enables the AW-SC to store unabsorbed light from visible to infrared wavelengths and emit green fluorescence to excite the N, S-CQDs in the dark. The optimal AW-SC achieves a power conversion efficiency (PCE) of 18.7% in the dark.

Nitrogen and sulfur co-doped carbon quantum dots as “on-off-on” fluorescence probes to detect Hg2+ and MnO4− and improving the photostability of Rhodamine B

BackgroundCarbon quantum dot (CQDs) are zero-dimensional carbon nanomaterials with a size of less than 10 nm CQDs are widely used in the field of ion detection by virtue of their fluorescence characteristics such as strong fluorescence intensity, good optical stability and tunable emission wavelength. Although the traditional atomic absorption method, electrochemical method and other metal ion detection methods are highly sensitive, the operation is complex, expensive and limited by the site. Therefore, we prepared the N, S-CQDs capable of detecting Hg2+ and MnO4− in water with the advantages of simple operation, low cost, and direct visual signal. ResultsN, S-CQDs with high-quantum yield (77.68%), uniform particle size (0.4 nm–2.6 nm) and green fluorescence were created utilizing a one-pot hydrothermal process with the precursors ASDA-Na4 and m-phenylenediamine. N, S-CQDs has good optical properties such as high fluorescence intensity, wavelength independence, up-conversion luminescence and fluorescence stability. We examined 27 common ions in water and found that the fluorescence of N, S-CQDs could be selectively quenched by Hg2+ and MnO4−, and the detection limits are 0.41 μM and 1.2 μM, respectively. The mechanism of quenching is further investigated. The fluorescence of N, S-CQDs-Hg2+ system can be restored by halogen ions (Cl−, Br−, I−), while the fluorescence of N, S-CQDs-MnO4- system can be partially restored by Fe2+. This forms an “on-off-on” mode of fluorescent probes. In addition, we also studied that trace amounts of N, S-CQDs can improve the photostability of RhB. SignificanceThe N, S-CQDs are fluorescent probes in an “on-off-on” mode. N, S-CQDs with green fluorescence (on) can be quenched by Hg2+ and MnO4− (off). The fluorescence quenched by Hg2+ can be restored by halogen ions again, while the fluorescence quenched by MnO4− can partially be restored (on). This ion detection method can be used to visually detect the two ions in the field, with the advantages of low cost, simple operation and visual intuition.

O-phenylenediamine Derived Fluorescent Carbon Quantum dots for Detection of Hg(II) in Environmental Water.

With the expansion of human activities, the consequent influx of mercury (Hg) into the food chain and the environment is seriously threatening human life. Herein, nitrogen and sulfur co-doped fluorescent carbon quantum dots (yCQDs) were prepared via a hydrothermal method using o-phenylenediamine (OPD) and taurine as precursors. The morphological characteristics as well as spectral features of yCQDs indicated that the photoluminescence mechanism should be the molecular state fluorophores of 2, 3-diaminophenothiazine (oxOPD), which is the oxide of OPD. The as-synthesized yCQDs exhibited sensitive recognition of Hg2+. According to the investigation in combination of UV-Vis absorption spectra, time-resolved fluorescence spectra and quantum chemical calculations, the abundant functional groups on the surface of yCQDs allowed Hg2+ to bind with yCQDs through various interactions, and the formed complexes significantly inhibited the absorption of excitation light, resulting in the static fluorescence quenching of yCQDs. The proposed yCQDs was utilized for Hg2+ sensing with the limit of detection calculated to be 4.50 × 10- 8M. Furthermore, the recognition ability of yCQDs for Hg2+ was estimated in tap water, lake water and bottled water, and the results indicated that yCQDs have potential applications in monitoring Hg2+.

Aminophenol functionalized carbon quantum dots as fluorescent sensor for nitroalkenes

To set up effective analysis method is important for environmental monitoring. In this work, the 4-aminophenol functionalized nitrogen and sulfur co-doped carbon quantum dots (AP-NSCDs) were synthesized based on the functionalization of NSCDs obtained by one-step hydrothermal method and used as a new fluorescent sensor for the determination of nitroalkene pesticide and medicine, such as nitenpyram, nizatidine and ranitidine. Nitroalkenes could quench the fluorescence of the functionalized carbon dots due to the fluorescence resonance energy transfer (FRET) principle. The sensor showed high sensitivity, selectivity, and stability, with a wide linear range of 0.05 ∼ 10 mg/L and a low detection limit of 0.02 mg/L. This sensor was successfully employed to detect nitenpyram in rice, orange and cabbage, and to determine nizatidine and ranitidine in serum, urine and river water as well. The developed method was rapid and sensitive, and had potential for monitoring the nitroalkene compounds in the environment and food.

Microwave prepared nitrogen and sulfur co-doped carbon quantum dots for rapid determination of ascorbic acid through a turn off–on strategy

A simple and eco-friendly microwave method was applied for the preparation of highly fluorescent nitrogen and sulfur co-doped carbon quantum dots (NS-CQDs) and used for the determination of ascorbic acid (ASC) in pharmaceutical dosage forms. The prepared NS-CQDs had bright blue fluorescence at a maximum emission wavelength of 440 nm, after excitation with 350 nm, with a quantum yield of 62.5 %. The developed NS-CQDs were prepared from citric acid and l-cysteine in one minute. The native fluorescence of NS-CQDs was quenched by ferric ions due to the formation of non-fluorescent CQDs/ Fe3+ complex. The quenched fluorescence could be restored by the addition of ASC due to the reducing properties of ASC which converts Fe3+ to Fe2+. The method was found linear over the concentration range of 2.0–100 μg/mL, with a limit of detection was 0.6 μg/mL and a coefficient of determination of 0.9965. The proposed method was cross-validated and statistically compared with a reported HPLC method. The results indicated that the developed method was greener, according to the analytical eco-scale and the green analytical procedure index (GAPI). The prepared NS-CQDs were used for spectrofluorometric determination of ASC in pharmaceutical dosage forms, with percentage recoveries ranging between 98 and 102 %, and relative standard deviations less than 2 %. The method was easy, rapid, reliable, and sensitive and did not require expensive reagents or sophisticated equipment.

Nitrogen and sulfur co-doped carbon quantum dots fluorescence quenching assay for detection of mercury (II)

Mercury is a highly toxic and potentially bioaccumulative heavy metal ion that can cause severe health problems in humans even at very low concentrations. Thus, the development of a simple, rapid, and sensitive assay for the effective detection of mercury ions at trace levels is of great importance. Here, nitrogen and sulfur co-doped carbon quantum dots (N,S-CQD) were synthesized by a simple hydrothermal treatment of chitosan in the presence of thiourea and citric acid with a quantum yield (QY) up to 33.0 % and used as a selective fluorescent probe to detect mercury ions (Hg2+). The effect of pH, ionic strength, and time on the fluorescence intensity of N,S-CQD were investigated and optimized. The synthesized N,S-CQD showed ultrasensitive ability to detect Hg2+ ions in the water samples, also in the presence of 11 interfering metal ions, with a low detection limit (∼4 nM) over a wide linear range from ∼5–160 nM. The sensing performance of N,S-CQD probe in real sample applications was evaluated by the detection of Hg2+ in lake water samples, which confirmed its potential application in environmental analysis.

Polyethylenimine-functionalized nitrogen and sulfur co-doped carbon dots as effective fluorescent probes for detection of Hg2+ ions

Surface modification of nitrogen and sulfur co-doped carbon quantum dots (N, S-CDs) were performed using cysteine and polyethylenimine as raw materials. The prepared N, S-CDs exhibited excitation-independent in the range of 300–380 nm. Furthermore, mercury(II) ions (Hg2+) can effectively quench the fluorescence intensity of the N, S-CDs. Based on this, we developed a fluorescence sensor with high sensitivity and selectivity to detect Hg2+. Under optimized conditions, the sensor showed good linearity in the range of 0–500 nM, and the limit of detection is 9.2 nM. Further, the sensor showed high sensitivity to Hg2+ in lake water and rice samples. The recovery of the Hg2+ in lake water and rice samples ranged between 98.2 % and 109.5 % with a relative standard deviation below 5.8 %. With outstanding sensitivity and selectivity, the fluorescence sensor provides a promising platform for monitoring Hg2+ in real samples.

Durable modulation of Zn(002) plane deposition via reproducible zincophilic carbon quantum dots towards low N/P ratio zinc-ion batteries.

Aqueous zinc-ion batteries (ZIBs) are promising candidates for next-generation energy storage systems due to their intrinsic safety, environmental friendliness, and low cost. However, the uncontrollable Zn dendrite growth during cycling is still a critical challenge for the long-term operation of ZIBs, especially under harsh lean-Zn conditions. Herein, we report nitrogen and sulfur-codoped carbon quantum dots (N,S-CDs) as zincophilic electrolyte additives to regulate the Zn deposition behaviors. The N,S-CDs with abundant electronegative groups can attract Zn2+ ions and co-deposit with Zn2+ ions on the anode surface, inducing a parallel orientation of the (002) crystal plane. The deposition of Zn preferentially along the (002) crystal direction fundamentally avoids the formation of Zn dendrites. Moreover, the co-depositing/stripping feature of N,S-CDs under an electric field force ensures the reproducible and long-lasting modulation of the Zn anode stability. Benefiting from these two unique modulation mechanisms, stable cyclability of the thin Zn anodes (10 and 20 μm) at a high depth of discharge (DOD) of 67% and high Zn||Na2V6O16·3H2O (NVO, 11.52 mg cm-2) full-cell energy density (144.98 W h Kg-1) at a record-low negative/positive (N/P) capacity ratio of 1.05 are achieved using the N,S-CDs as an additive in ZnSO4 electrolyte. Our findings not only offer a feasible solution for developing actual high-energy density ZIBs but also provide in-depth insights into the working mechanism of CDs in regulating Zn deposition behaviors.